Still's disease

Still’s disease is a multisystem inflammatory process characterized by daily episodes of fever, rash, arthralgia/arthritis and myalgia, in adults aged 15 and 35. It takes its name from the English pediatrician George Still, who described it as juvenile rheumatoid arthritis but in adults.

Etiology

Underlying causes of the disease, or factors that influence, predispose or precipitate its onset.

Pathogenesis

Decription of how the process unfolds, that is, how it causes the body to produce the appearance of the disease.

Pathology

Description of microscopic and macroscopic lesions objectively as a result of the disease.

Clinical features

Fever
Sore throat
Macular or maculopapular rash
Arthritis and myalgias
Cardiopulmonary Manifestations
Mobile and tender lymph nodes, the most affected with cervical level.

Diagnosis

Guidance on the history, physical examination, diagnostic test.

Differential diagnosis

Hepatitis infections, coxsackie, rubella, CMV.
Granulomatous processes such as granulomatous hepatitis, idiopathic sarcoidosis and Crohn’s disease.
Vasculitis: Wegener, Takayasu
Leukemia

Treatment

Aspirin
Indomethacin
Corticosteroids such as prednisone
Methotrexate
OTHER NSAIDs

Prognosis

Natural history of the disease with and without treatment, and potential complications of the disease and available treatments. Morbidity and mortality of the disease.

Prophylaxis

All the methods available to prevent or avoid the appearance of the disease.